Imaging methodologies for systems biology
نویسندگان
چکیده
منابع مشابه
The methodologies of systems biology
In this book on philosophical aspects of systems biology, this chapter summarizes the philosophical status of a variety of sciences. Biology, physics and molecular biology offer particular contrast here. It is contended that philosophy and methodology should be determined substantially by the degree of complexity of the system under study. Some of the new experimental methods that have made sys...
متن کاملImaging in Systems Biology
Most systems biology approaches involve determining the structure of biological circuits using genomewide "-omic" analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal. Here, we discuss the power of integrating imaging tools with more conventional -omic approaches to analyze the biological circuits of ...
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تخمین دقیق مشخصات کانال در سیستم های مخابراتی یک امر مهم محسوب می گردد. این امر به ویژه در کانال های بیسیم با خاصیت فرکانس گزینی و زمان گزینی شدید، چالش بزرگی است. مقالات متعدد پر از روش های مبتکرانه ای برای طراحی و آنالیز الگوریتم های تخمین کانال است که بیشتر آنها از روش های خاصی استفاده می کنند که یا دارای عملکرد خوب با پیچیدگی محاسباتی بالا هستند و یا با عملکرد نه چندان خوب پیچیدگی پایینی...
Live cell imaging and systems biology.
Much of the experimental data used to construct mathematical models of molecular networks are derived from in vitro measurements. However, there is increasing evidence that in vitro measurements fail to capture both the complexity and the individuality found in single, living cells. These limitations can be overcome by live cell microscopy which is evolving to enable in vivo biochemistry. Here,...
متن کاملInvited Talk: Imaging-Based Systems Biology
Arguably the most significant contribution of the human genome project is that we can now build a recombinant construct of every gene and every promotor in C. elegans (worm), D. melanogaster (fly), M. musculus (mouse), and H. sapiens (human). These include fluorescent proteins and other markers that can be induced at controlled time points via a change in temperature, light, or chemistry. Combi...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2014
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.29152